Wait and See

One blood test. One number. Clarity into MS disease activity, grounded in biology. So you and your provider can make data-backed decisions together.

29,000+

Scores delivered

500+

Prescribers

20,000+

Patients already empowered

Available through Quest Diagnostics - 7,000+ blood draw locations nationwide

See what’s happening now

Not just what’s already happened

Today's standard of care shows damage already done. The Octave Multiple Sclerosis Disease Activity (MSDA) Test reveals active disease biology, giving providers and patients the objective insights to adjust MS therapy with confidence - together.

Clinically validated

Backed by published research, the MSDA Test measures 18 biomarkers to detect MS disease activity and inform real-world care decisions.

Clarity at a glance

One simple number (1-10) gives providers and patients a clear read on current disease activity and tracking it over time helps catch changes early and confirm if the treatment is working.

Act sooner

Today’s standard of care measures damage already done. The MSDA Test reveals what’s happening now, so providers and patients can act sooner.

One draw. One number.

Using AI, the Octave MSDA Test analyzes 18 of your biomarkers, clinical context, and data from thousands of patients to generate a personalized score from 1 to 10.
Here’s how it works:

1 - 4

A low score indicates low disease activity. Continued monitoring helps confirm the trend and catch any changes early.

Low Score

4.5-7

A moderate score indicates some disease activity. Tracking activity over time helps surface changes worth discussing.

Moderate Score

7.5-10

A high score indicates elevated disease activity. Repeat testing supports informed care decisions.

High Score

What the score reveals

The MSDA Test measures the biology of MS disease activity in real time - detecting changes that may not yet appear in symptoms or on imaging.

How results fit into care

Better data, better insight, better care. The MSDA Test supports clinical decision‑making by giving providers an objective measure of disease activity to  interpret alongside symptoms, medical history, and imaging.

Why repeat testing matters

A single score is a snapshot. Tracking activity over time reveals trends, surfaces changes early, and informs whether the current care plan is working or needs revisiting.

MS disease activity

Available now

MS disease progression

In development

Parkinson’s Disease

In development

Helping patients find answers where there were none.

MS is just the beginning. Octave is building the future of precision neurology, where no one faces a neurological condition without answers.

The mission: bring clarity and confidence to providers and patients navigating these diseases, with personalized insight across a range of clinical scenarios.

Detect disease activity before symptoms appear

Track disease activity over time to inform decisions

Guide therapy decisions with objective data

Support timely action when it matters most

Decision-making backed by

rigorous science

Peer-reviewed research and real-world evidence from leading MS centers and clinical practices

SINGLE-TEST IMPACT

60%

Clinicians agreed one MSDA
result informed decisions

LONGITUDINAL IMPACT

69%

Clinicians agreed MSDA results
informed decisions over time

TREATMENT DECISIONS CHANGED

1 in 5

Documented decision changes
after MSDA testing

MULTI-PROTEIN PRECISION

18

Protein biomarkers
in one score

Explore the Clinical Resource Center

Peer-reviewed publications, poster abstracts, and scientific presentations from leading MS centers

Held to the highest laboratory standards

CLIA Certified

Federal certification required
for all clinical labs

CAP Accredited

Gold-standard quality
accreditation

NY State CLEP

Approved under the nation’s most
stringent state lab oversight

Easy does it

Easy to afford

All insurances are accepted. The Octave Cares program provides financial assistance for patients who qualify.

See if you qualify

Easy to access

Once your provider orders the MSDA Test, a simple blood draw can be completed at any of 7,000+ Quest Diagnostics locations nationwide.

Find a Quest location

Easy to understand

A score from 1 to 10 reflects current disease activity. Low scores indicate stability. Higher scores prompt timely conversations about care.

See a sample report

The difference that
insights make

Hear from patients and providers who’ve experienced the difference precision data has made for them

Patient

As a clinician, researcher, advocate and MS patient, I live the challenges of managing MS. The MSDA Test has given me invaluable insights that helped me navigate my own disease while also providing tremendous peace of mind. The Octave MSDA Test is the compass to care that we have been seeking. The ACP is proud of our long-standing partnership with Octave Bioscience. Our collaboration enabled the demonstration of proteomic associations with clinically defined relapse in multiple sclerosis and was crucial for developing the MSDA Test.

Stephanie Buxhoeveden

Diagnosed 2020

CSO, Accelerated Cure Project for Multiple Sclerosis

Patient

I’ve lived with MS for 22 years. I spent five of them in a wheelchair. I’m not interested in blind spots. The MRI tells you what happened. The MSDA Test tells you what to ask next. Now I test quarterly and bring the results to my neurologist. That’s the tool I never had before.

Kent Jones @ThatGuyWithMS.

Community Council Chairperson, National MS Society

Neurologist

Establishing a baseline and monitoring disease activity at a regular cadence gives me objective insight I didn’t have before. The data helps me see what’s happening beneath the surface, so I can have more informed conversations with my patients about their care. Longitudinal testing with the MSDA Test has become my standard of care.

Alexandra Filippakis, DO.

Board Certified Neurologist

Greenleaf Neurology

Patient

My MRI scans have been stable for two years. My body tells a different story. The Octave MSDA Test helped bridge that gap - turning what I felt but couldn't prove into data I could bring to my neurologist. As a coach, I know you can’t improve what you can’t measure. As an MS patient and advocate, I believe every person living with this disease deserves tools that show the full picture. You are more than your MRI.

Denise Schnieders @MSdopaminedressed.

MS patient advocate

Teacher & Coach

Ready to take control?

Join 20,000+ MS patients who track their disease activity with confidence. Stop guessing. Start knowing.